AGR3 antibody

Catalog No. ABIN614769

The Mouse Monoclonal anti-AGR3 antibody (Clone AGR3-2) (ABIN614769) specifically detects AGR3 in WB, FACS and IHC (fro). The antibody is reactive with Human samples.

Quick Overview for AGR3 antibody (ABIN614769)

Target: AGR3 (Anterior Gradient 3 (AGR3))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This AGR3 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: AGR3-2

Product Details anti-AGR3 Antibody

Specificity: This antibody recognizes epitope QYSQALKKV within AGR3 (AG3) protein (19-20 kDa), secreted cytoplasmic protein which can serve as a marker of carcinogenesis.

Cross-Reactivity (Details): Species reactivity (tested):Human

Purification: Protein-A affinity chromatography

Purity: > 95 % pure by SDS-PAGE

Immunogen: Purified human AGR3 protein

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS) containing 15 mM sodium azide and 0.2 % (w/v) high-grade protease free Bovine Serum Albumin (BSA) as a stabilizing agent

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Target Details for AGR3

Target: AGR3 (Anterior Gradient 3 (AGR3))

Alternative Name: AGR3

Background: AGR3 (Anterior Gradient 3) protein, also known as AG3 (hAG-3, HAG3 in human), or BCMP11, is a secreted cytoplasmic protein which is involved in metastasis induction and p53 tumour supressor inhibition. It may serve as molecular marker and potential therapeutic target for hormone-responsive breast tumours. Its Xenopus homolog is associated with anteroposterior fate determination during early development.Synonyms: Anterior gradient protein 3 homolog, BCMP11, HAG-3, HAG3, breast cancer membrane protein 11

Gene ID: 155465, 9606

UniProt: Q8TD06