SIGLEC5 antibody (AA 452-551)

Catalog No. ABIN6147761

The Rabbit Polyclonal anti-SIGLEC5 antibody has been validated for WB. It is suitable to detect SIGLEC5 in samples from Human.

Quick Overview for SIGLEC5 antibody (AA 452-551) (ABIN6147761)

Target: SIGLEC5 (Sialic Acid Binding Ig-Like Lectin 5 (SIGLEC5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SIGLEC5 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SIGLEC5 Antibody

Binding Specificity: AA 452-551

Sequence: ICLCLIFFLI VKARRKQAAG RPEKMDDEDP IMGTITSGSR KKPWPDSPGD QASPPGDAPP LEEQKELHYA SLSFSEMKSR EPKDQEAPST TEYSEIKTSK

Cross-Reactivity: Human

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 452-551 of human SIGLEC5 (NP_003821.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for SIGLEC5

Target: SIGLEC5 (Sialic Acid Binding Ig-Like Lectin 5 (SIGLEC5))

Alternative Name: SIGLEC5

Background: This gene encodes a member of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. These cell surface lectins are characterized by structural motifs in the immunoglobulin (Ig)-like domains and sialic acid recognition sites in the first Ig V set domain. The encoded protein is a member of the CD33-related subset of Siglecs and inhibits the activation of several cell types including monocytes, macrophages and neutrophils. Binding of group B Streptococcus (GBS) to the encoded protein plays a role in GBS immune evasion.,SIGLEC5,CD170,CD33L2,OB-BP2,OBBP2,SIGLEC-5,Immunology & Inflammation,CD markers,SIGLEC5

Molecular Weight: 60 kDa

Gene ID: 8778

UniProt: O15389