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CD81 antibody

This anti-CD81 antibody is a Mouse Monoclonal antibody detecting CD81 in FACS, WB, IP, IF, Func and IHC (p). Suitable for Human, Rabbit and Cat. This Primary Antibody has been cited in 1 publication.
Catalog No. ABIN614802

Quick Overview for CD81 antibody (ABIN614802)

Target

See all CD81 Antibodies
CD81

Reactivity

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Human, Rabbit, Cat

Host

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  • 93
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Mouse

Clonality

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Monoclonal

Conjugate

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  • 2
  • 1
  • 1
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This CD81 antibody is un-conjugated

Application

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Flow Cytometry (FACS), Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (IF), Functional Studies (Func), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone

M38
  • Specificity

    This antibody reacts with CD81, a 25 kDa member of the tetraspanin family, expressed on majority of cells.

    Cross-Reactivity (Details)

    Species reactivity (tested):Human, Feline (Cat), Rabbit

    Purification

    Protein-A affinity chromatography

    Purity

    > 95 % pure by SDS-PAGE

    Immunogen

    MOLT-4 (human T-ALL cell line)

    Isotype

    IgG1
  • Application Notes

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Concentration

    1.0 mg/mL

    Buffer

    Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4

    Preservative

    Sodium azide

    Precaution of Use

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handling Advice

    Avoid repeated freezing and thawing.

    Storage

    4 °C/-20 °C

    Storage Comment

    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • Escola, Kleijmeer, Stoorvogel, Griffith, Yoshie, Geuze: "Selective enrichment of tetraspan proteins on the internal vesicles of multivesicular endosomes and on exosomes secreted by human B-lymphocytes." in: The Journal of biological chemistry, Vol. 273, Issue 32, pp. 20121-7, (1998) (PubMed).

  • Target

    CD81

    Alternative Name

    CD81 / TAPA1

    Background

    CD81 (TAPA-1), a member of the tetraspanin family, is expressed on virtually all nucleated cells, but above all on germinal center B cells. CD81 forms complexes with other tetraspanin proteins, integrins, coreceptors, MHC class I and II molecules, and influences adhesion, morphology, activation, proliferation and differentiation of B, T and other cells - e.g. in muscles CD81 promotes cell fusion and myotube maintenance. CD81 has been also identified as a receptor for the hepatitis C virus.Synonyms: 26 kDa cell surface protein TAPA-1, Target of the antiproliferative antibody 1

    Gene ID

    975

    NCBI Accession

    NP_004347

    UniProt

    P60033

    Pathways

    Inositol Metabolic Process, Hepatitis C
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