SMARCB1 antibody (AA 77-376)

Catalog No. ABIN6148107

The Rabbit Polyclonal anti-SMARCB1 antibody has been validated for WB, IHC, IF and IP. It is suitable to detect SMARCB1 in samples from Human.

Quick Overview for SMARCB1 antibody (AA 77-376) (ABIN6148107)

Target: SMARCB1 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily B, Member 1 (SMARCB1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SMARCB1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

Product Details anti-SMARCB1 Antibody

Binding Specificity: AA 77-376

Sequence: TSVTLLKASE VEEILDGNDE KYKAVSISTE PPTYLREQKA KRNSQWVPTL PNSSHHLDAV PCSTTINRNR MGRDKKRTFP LCFDDHDPAV IHENASQPEV LVPIRLDMEI DGQKLRDAFT WNMNEKLMTP EMFSEILCDD LDLNPLTFVP AIASAIRQQI ESYPTDSILE DQSDQRVIIK LNIHVGNISL VDQFEWDMSE KENSPEKFAL KLCSELGLGG EFVTTIAYSI RGQLSWHQKT YAFSENPLPT VEIAIRNTGD ADQWCPLLET LTDAEMEKKI RDQDRNTRRM RRLANTAPAW

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 77-376 of human SMARCB1/SNF5 (NP_001007469.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200,IP,1:50 - 1:200

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for SMARCB1

Target: SMARCB1 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily B, Member 1 (SMARCB1))

Alternative Name: SMARCB1

Background: The protein encoded by this gene is part of a complex that relieves repressive chromatin structures, allowing the transcriptional machinery to access its targets more effectively. The encoded nuclear protein may also bind to and enhance the DNA joining activity of HIV-1 integrase. This gene has been found to be a tumor suppressor, and mutations in it have been associated with malignant rhabdoid tumors. Alternatively spliced transcript variants have been found for this gene.,SMARCB1,BAF47,CSS3,INI1,MRD15,PPP1R144,RDT,RTPS1,SNF5,SNF5L1,SWNTS1,Sfh1p,Snr1,hSNFS,Epigenetics & Nuclear Signaling,Chromatin Remodeling,Cancer,Tumor suppressors,Cell Biology & Developmental Biology,Apoptosis,SMARCB1

Molecular Weight: 43 kDa/44 kDa

Gene ID: 6598

UniProt: Q12824