SMEK1 antibody (AA 395-594)

Catalog No. ABIN6148130

The Rabbit Polyclonal anti-SMEK1 antibody has been validated for WB, IHC and IF. It is suitable to detect SMEK1 in samples from Human.

Quick Overview for SMEK1 antibody (AA 395-594) (ABIN6148130)

Target: SMEK1 (Serine/threonine-Protein Phosphatase 4 Regulatory Subunit 3A (SMEK1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SMEK1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-SMEK1 Antibody

Binding Specificity: AA 395-594

Sequence: VQTFKGLKLR FEQQRERQDN PKLDSMRSIL RNHRYRRDAR TLEDEEEMWF NTDEDDMEDG EAVVSPSDKT KNDDDIMDPI SKFMERKKLK ESEEKEVLLK TNLSGRQSPS FKLSLSSGTK TNLTSQSSTT NLPGSPGSPG SPGSPGSPGS VPKNTSQTAA ITTKGGLVGL VDYPDDDEDD DEDEDKEDTL PLSKKAKFDS

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 395-594 of human SMEK1 (NP_001271210.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:200

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for SMEK1

Target: SMEK1 (Serine/threonine-Protein Phosphatase 4 Regulatory Subunit 3A (SMEK1))

Alternative Name: SMEK1

Background: Regulatory subunit of serine/threonine-protein phosphatase 4. May regulate the activity of PPP4C at centrosomal microtubule organizing centers. The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AX phosphorylated on 'Ser-140' (gamma-H2AX generated during DNA replication and required for DNA DSB repair.,PPP4R3A,FLFL1,KIAA2010,MSTP033,PP4R3,PP4R3A,SMEK1,smk-1,smk1,Epigenetics & Nuclear Signaling,SMEK1

Molecular Weight: 62 kDa/67 kDa/93 kDa/95 kDa

Gene ID: 55671

UniProt: Q6IN85

Pathways: Regulation of Carbohydrate Metabolic Process