SMYD5 antibody

Catalog No. ABIN6148173

This Rabbit Polyclonal antibody specifically detects SMYD5 in WB, IHC and IF. It exhibits reactivity toward Human.

Quick Overview for SMYD5 antibody (ABIN6148173)

Target: SMYD5 (SMYD Family Member 5 (SMYD5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SMYD5 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-SMYD5 Antibody

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant protein of human SMYD5

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for SMYD5

Target: SMYD5 (SMYD Family Member 5 (SMYD5))

Alternative Name: SMYD5

Background: Histone methyltransferase that specifically trimethylates 'Lys-20' of histone H4 to form trimethylated histone H4 lysine 20 (H4K20me3 which represents a specific tag for epigenetic transcriptional repression (By similarity. In association with the NCoR corepressor complex, is involved in the repression of toll-like receptor 4 (TLR4-target inflammatory genes in macrophages by catalyzing the formation of H4K20me3 at the gene promoters (By similarity. Plays an important role in embryonic stem (ES cell self-renewal and differentiation (By similarity. Promotes ES cell maintenance by silencing differentiation genes through deposition of H4K20me3 marks (By similarity. Maintains genome stability of ES cells during differentiation through regulation of heterochromatin formation and repression of endogenous repetitive DNA elements by depositing H4K20me3 marks.,SMYD5,NN8-4AG,RAI15,RRG1,ZMYND23,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,SMYD5

Molecular Weight: 47 kDa

Gene ID: 10322

UniProt: Q6GMV2