SNAIL antibody (C-Term)

Catalog No. ABIN6148177

This anti-SNAIL antibody is a Rabbit Polyclonal antibody detecting SNAIL in WB and IHC. Suitable for Human. This Primary Antibody has been cited in 1 publication.

Quick Overview for SNAIL antibody (C-Term) (ABIN6148177)

Target: SNAIL (SNAI1)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SNAIL antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-SNAIL Antibody

Binding Specificity: C-Term

Sequence: RTHTGEKPFS CPHCSRAFAD RSNLRAHLQT HSDVKKYQCQ ACARTFSRMS LLHKHQESGC SGCPR

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 200 to the C-terminus of human Snail (NP_005976.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:100

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

References for anti-SNAIL antibody (ABIN6148177)

Zheng, Guan, Jia, Wang, Pang, Lv, Xiao, Wang, Zhang, Xue: "The coordinated roles of miR-26a and miR-30c in regulating TGFβ1-induced epithelial-to-mesenchymal transition in diabetic nephropathy." in: Scientific reports, Vol. 6, pp. 37492, (2018) (PubMed).

Target Details for SNAIL

Target: SNAIL (SNAI1)

Alternative Name: SNAI1

Background: The Drosophila embryonic protein snail is a zinc finger transcriptional repressor which downregulates the expression of ectodermal genes within the mesoderm. The nuclear protein encoded by this gene is structurally similar to the Drosophila snail protein, and is also thought to be critical for mesoderm formation in the developing embryo. At least two variants of a similar processed pseudogene have been found on chromosome 2.,SNAI1,SLUGH2,SNA,SNAH,SNAIL,SNAIL1,dJ710H13.1,Epigenetics & Nuclear Signaling,Transcription Factors,Cancer,Cardiovascular,Heart,Cardiogenesis,SNAI1

Molecular Weight: 29 kDa

Gene ID: 6615

UniProt: O95863

Pathways: Negative Regulation of intrinsic apoptotic Signaling