SOS1 antibody (AA 1034-1333)

Catalog No. ABIN6148283

The Rabbit Polyclonal anti-SOS1 antibody has been validated for WB. It is suitable to detect SOS1 in samples from Human.

Quick Overview for SOS1 antibody (AA 1034-1333) (ABIN6148283)

Target: SOS1 (Son of Sevenless Homolog 1 (SOS1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SOS1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SOS1 Antibody

Binding Specificity: AA 1034-1333

Sequence: PLKSPGVRPS NPRPGTMRHP TPLQQEPRKI SYSRIPESET ESTASAPNSP RTPLTPPPAS GASSTTDVCS VFDSDHSSPF HSSNDTVFIQ VTLPHGPRSA SVSSISLTKG TDEVPVPPPV PPRRRPESAP AESSPSKIMS KHLDSPPAIP PRQPTSKAYS PRYSISDRTS ISDPPESPPL LPPREPVRTP DVFSSSPLHL QPPPLGKKSD HGNAFFPNSP SPFTPPPPQT PSPHGTRRHL PSPPLTQEVD LHSIAGPPVP PRQSTSQHIP KLPPKTYKRE HTHPSMHRDG PPLLENAHSS

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1034-1333 of human SOS1 (NP_005624.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for SOS1

Target: SOS1 (Son of Sevenless Homolog 1 (SOS1))

Alternative Name: SOS1

Background: This gene encodes a protein that is a guanine nucleotide exchange factor for RAS proteins, membrane proteins that bind guanine nucleotides and participate in signal transduction pathways. GTP binding activates and GTP hydrolysis inactivates RAS proteins. The product of this gene may regulate RAS proteins by facilitating the exchange of GTP for GDP. Mutations in this gene are associated with gingival fibromatosis 1 and Noonan syndrome type 4.,SOS1,GF1,GGF1,GINGF,HGF,NS4,Cancer,Signal Transduction,G protein signaling,Signal Transduction,G2/M DNA Damage Checkpoint,ErbB-HER Signaling Pathway,MAPK-Erk Signaling Pathway,MAPK-JNK Signaling Pathway,Cell Biology & Developmental Biology,TGF-b-Smad Signaling Pathway,Endocrine & Metabolism,Insulin Receptor Signaling Pathway,Immunology & Inflammation,B Cell Receptor Signaling Pathway,T Cell Receptor Signaling Pathway,SOS1

Molecular Weight: 36 kDa/152 kDa

Gene ID: 6654

UniProt: Q07889

Pathways: RTK Signaling, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Hepatitis C, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling