SPDEF/PSE antibody (AA 1-335)

Catalog No. ABIN6148332

The Rabbit Polyclonal anti-SPDEF/PSE antibody has been validated for WB, IHC and IF. It is suitable to detect SPDEF/PSE in samples from Human.

Quick Overview for SPDEF/PSE antibody (AA 1-335) (ABIN6148332)

Target: SPDEF/PSE (SPDEF) (Proximal Sequence Element 1 (SPDEF))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SPDEF/PSE antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-SPDEF/PSE Antibody

Binding Specificity: AA 1-335

Sequence: MGSASPGLSS VSPSHLLLPP DTVSRTGLEK AAAGAVGLER RDWSPSPPAT PEQGLSAFYL SYFDMLYPED SSWAAKAPGA SSREEPPEEP EQCPVIDSQA PAGSLDLVPG GLTLEEHSLE QVQSMVVGEV LKDIETACKL LNITADPMDW SPSNVQKWLL WTEHQYRLPP MGKAFQELAG KELCAMSEEQ FRQRSPLGGD VLHAHLDIWK SAAWMKERTS PGAIHYCAST SEESWTDSEV DSSCSGQPIH LWQFLKELLL KPHSYGRFIR WLNKEKGIFK IEDSAQVARL WGIRKNRPAM NYDKLSRSIR QYYKKGIIRK PDISQRLVYQ FVHPI

Cross-Reactivity: Human, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-335 of human SPDEF (NP_036523.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:1000,IHC,1:50 - 1:200,IF,1:50 - 1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for SPDEF/PSE

Target: SPDEF/PSE (SPDEF) (Proximal Sequence Element 1 (SPDEF))

Alternative Name: SPDEF

Background: The protein encoded by this gene belongs to the ETS family of transcription factors. It is highly expressed in the prostate epithelial cells, and functions as an androgen-independent transactivator of prostate-specific antigen (PSA) promoter. Higher expression of this protein has also been reported in brain, breast, lung and ovarian tumors, compared to the corresponding normal tissues, and it shows better tumor-association than other cancer-associated molecules, making it a more suitable target for developing specific cancer therapies. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.,SPDEF,PDEF,bA375E1.3,Epigenetics & Nuclear Signaling,Transcription Factors,Cancer,Tumor biomarkers,SPDEF

Molecular Weight: 35 kDa/37 kDa

Gene ID: 25803

UniProt: O95238