SREBF2 antibody (AA 1-220)

Catalog No. ABIN6148430

This Rabbit Polyclonal antibody specifically detects SREBF2 in WB, IHC and IF. It exhibits reactivity toward Human.

Quick Overview for SREBF2 antibody (AA 1-220) (ABIN6148430)

Target: SREBF2 (Sterol Regulatory Element Binding Transcription Factor 2 (SREBF2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SREBF2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-SREBF2 Antibody

Binding Specificity: AA 1-220

Sequence: MDDSGELGGL ETMETLTELG DELTLGDIDE MLQFVSNQVG EFPDLFSEQL CSSFPGSGGS GSSSGSSGSS SSSSNGRGSS SGAVDPSVQR SFTQVTLPSF SPSAASPQAP TLQVKVSPTS VPTTPRATPI LQPRPQPQPQ PQTQLQQQTV MITPTFSTTP QTRIIQQPLI YQNAATSFQV LQPQVQSLVT SSQVQPVTIQ QQVQTVQAQR VLTQTANGTL

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human SREBF2 (NP_004590.2).

Isotype: IgG

Application Details

Application Notes: WB,1:1000 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for SREBF2

Target: SREBF2 (Sterol Regulatory Element Binding Transcription Factor 2 (SREBF2))

Alternative Name: SREBF2

Background: This gene encodes a member of the a ubiquitously expressed transcription factor that controls cholesterol homeostasis by regulating transcription of sterol-regulated genes. The encoded protein contains a basic helix-loop-helix-leucine zipper (bHLH-Zip) domain and binds the sterol regulatory element 1 motif. Alternate splicing results in multiple transcript variants.,SREBF2,SREBP-2,SREBP2,bHLHd2,Epigenetics & Nuclear Signaling,Transcription Factors,Cancer,Endocrine & Metabolism,Lipid Metabolism,Cholesterol Metabolism,Warburg Effect,Cardiovascular,Lipids,SREBF2

Molecular Weight: 73 kDa/123 kDa

Gene ID: 6721

UniProt: Q12772

Pathways: Regulation of Lipid Metabolism by PPARalpha