STXBP4 antibody (AA 344-553)

Catalog No. ABIN6148681

This anti-STXBP4 antibody is a Rabbit Polyclonal antibody detecting STXBP4 in WB and IHC. Suitable for Human.

Quick Overview for STXBP4 antibody (AA 344-553) (ABIN6148681)

Target: STXBP4 (Syntaxin Binding Protein 4 (STXBP4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STXBP4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-STXBP4 Antibody

Binding Specificity: AA 344-553

Sequence: EETRALRSRI HLAEAAQRQA HGMEMDYEEV IRLLEAKITE LKAQLADYSD QNKESVQDLK KRIMVLDCQL RKSEMARKTF EASTEKLLHF VEAIQEVFSD NSTPLSNLSE RRAVLASQTS LTPLGRNGRS IPATLALESK ELVKSVRALL DMDCLPYGWE EAYTADGIKY FINHVTQTTS WIHPVMSVLN LSRSEENEED CSRELPNQKS

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 344-553 of human STXBP4 (NP_848604.3).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for STXBP4

Target: STXBP4 (Syntaxin Binding Protein 4 (STXBP4))

Alternative Name: STXBP4

Background: Plays a role in the translocation of transport vesicles from the cytoplasm to the plasma membrane. Inhibits the translocation of SLC2A4 from intracellular vesicles to the plasma membrane by STX4A binding and preventing the interaction between STX4A and VAMP2. Stimulation with insulin disrupts the interaction with STX4A, leading to increased levels of SLC2A4 at the plasma membrane. May also play a role in the regulation of insulin release by pancreatic beta cells after stimulation by glucose (By similarity.,STXBP4,Synip,Signal Transduction,Endocrine & Metabolism,Insulin Receptor Signaling Pathway,STXBP4

Molecular Weight: 26 kDa/61 kDa

Gene ID: 252983

UniProt: Q6ZWJ1