STXBP4 antibody (N-Term)

Catalog No. ABIN2790280

The Rabbit Polyclonal anti-STXBP4 antibody is suitable to detect STXBP4 in samples from Human. It has been validated for WB.

Quick Overview for STXBP4 antibody (N-Term) (ABIN2790280)

Target: STXBP4 (Syntaxin Binding Protein 4 (STXBP4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STXBP4 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-STXBP4 Antibody

Binding Specificity: N-Term

Purpose: STXBP4 Antibody - N-terminal region

Sequence: SVNKESMIGV SFEEAKSIIT GAKLRLESAW EIAFIRQKSD NIQPENLSCT

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against STXBP4. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human STXBP4

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP65839-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for STXBP4

Target: STXBP4 (Syntaxin Binding Protein 4 (STXBP4))

Alternative Name: STXBP4

Background:

Background Information: STXBP4 plays a role in the translocation of transport vesicles from the cytoplasm to the plasma membrane. STXBP4 inhibits the translocation of SLC2A4 from intracellular vesicles to the plasma membrane by STX4A binding and preventing the interaction between STX4A and VAMP2. Stimulation with insulin disrupts the interaction with STX4A, leading to increased levels of SLC2A4 at the plasma membrane. STXBP4 may also play a role in the regulation of insulin release by pancreatic beta cells after stimulation by glucose.

Gene Name: Syntaxin binding protein 4

Alternative Symbols: Synip

Protein Name: Syntaxin-binding protein 4

Molecular Weight: 62kDa

Gene ID: 252983

NCBI Accession: NP_848604

UniProt: Q6ZWJ1