SUFUH antibody (AA 325-484)

Catalog No. ABIN6148692

This anti-SUFUH antibody is a Rabbit Polyclonal antibody detecting SUFUH in WB, IHC and IF. Suitable for Human.

Quick Overview for SUFUH antibody (AA 325-484) (ABIN6148692)

Target: SUFUH (Suppressor of Fused Homolog (SUFUH))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SUFUH antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-SUFUH Antibody

Binding Specificity: AA 325-484

Sequence: PPINPQRQNG LAHDRAPSRK DSLESDSSTA IIPHELIRTR QLESVHLKFN QESGALIPLC LRGRLLHGRH FTYKSITGDM AITFVSTGVE GAFATEEHPY AAHGPWLQIL LTEEFVEKML EDLEDLTSPE EFKLPKEYSW PEKKLKVSIL PDVVFDSPLH

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 325-484 of human SUFU (NP_057253.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for SUFUH

Target: SUFUH (Suppressor of Fused Homolog (SUFUH))

Alternative Name: SUFU

Background: The Hedgehog signaling pathway plays an important role in early human development. The pathway is a signaling cascade that plays a role in pattern formation and cellular proliferation during development. This gene encodes a negative regulator of the hedgehog signaling pathway. Defects in this gene are a cause of medulloblastoma. Alternative splicing results in multiple transcript variants.,SUFU,PRO1280,SUFUH,SUFUXL,Epigenetics & Nuclear Signaling,Cancer,Tumor suppressors,Cell Biology & Developmental Biology,Apoptosis,Hedgehog Signaling Pathway,SUFU

Molecular Weight: 47 kDa/52 kDa/53 kDa

Gene ID: 51684

UniProt: Q9UMX1

Pathways: Hedgehog Signaling, Tube Formation, Maintenance of Protein Location