TCP1 alpha/CCTA antibody (AA 307-556)

Catalog No. ABIN6148956

The Rabbit Polyclonal anti-TCP1 alpha/CCTA antibody (ABIN6148956) specifically detects TCP1 alpha/CCTA in WB and IHC. The antibody is reactive with Human samples.

Quick Overview for TCP1 alpha/CCTA antibody (AA 307-556) (ABIN6148956)

Target: TCP1 alpha/CCTA (TCP1) (T-Complex 1 (TCP1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TCP1 alpha/CCTA antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-TCP1 alpha/CCTA Antibody

Binding Specificity: AA 307-556

Sequence: AVRRVLKRDL KRIAKASGAT ILSTLANLEG EETFEAAMLG QAEEVVQERI CDDELILIKN TKARTSASII LRGANDFMCD EMERSLHDAL CVVKRVLESK SVVPGGGAVE AALSIYLENY ATSMGSREQL AIAEFARSLL VIPNTLAVNA AQDSTDLVAK LRAFHNEAQV NPERKNLKWI GLDLSNGKPR DNKQAGVFEP TIVKVKSLKF ATEAAITILR IDDLIKLHPE SKDDKHGSYE DAVHSGALND

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 307-556 of human TCP1 (NP_110379.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for TCP1 alpha/CCTA

Target: TCP1 alpha/CCTA (TCP1) (T-Complex 1 (TCP1))

Alternative Name: TCP1

Background: The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants of this gene, encoding different isoforms, have been characterized. In addition, three pseudogenes that appear to be derived from this gene have been found.,TCP1,CCT-alpha,CCT1,CCTa,D6S230E,TCP-1-alpha,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Microfilaments,TCP1

Molecular Weight: 60 kDa

Gene ID: 6950

UniProt: P17987