TDRKH antibody (AA 36-355)

Catalog No. ABIN6148980

This Rabbit Polyclonal antibody specifically detects TDRKH in WB. It exhibits reactivity toward Human.

Quick Overview for TDRKH antibody (AA 36-355) (ABIN6148980)

Target: TDRKH (Tudor and KH Domain Containing (TDRKH))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TDRKH antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TDRKH Antibody

Binding Specificity: AA 36-355

Sequence: RYRESREERL TFVGEDDIEI EMRVPQEAVK LIIGRQGANI KQLRKQTGAR IDVDTEDVGD ERVLLISGFP VQVCKAKAAI HQILTENTPV SEQLSVPQRS VGRIIGRGGE TIRSICKASG AKITCDKESE GTLLLSRLIK ISGTQKEVAA AKHLILEKVS EDEELRKRIA HSAETRVPRK QPISVRREDM TEPGGAGEPA LWKNTSSSME PTAPLVTPPP KGGGDMAVVV SKEGSWEKPS DDSFQKSEAQ AIPEMPMFEI PSPDFSFHAD EYLEVYVSAS EHPNHFWIQI VGSRSLQLDK LVNEMTQHYE NSVPEDLTVH

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 36-355 of human TDRKH (NP_001077432.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for TDRKH

Target: TDRKH (Tudor and KH Domain Containing (TDRKH))

Alternative Name: TDRKH

Background: Participates in the primary piRNA biogenesis pathway and is required during spermatogenesis to repress transposable elements and prevent their mobilization, which is essential for the germline integrity. The piRNA metabolic process mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Required for the final steps of primary piRNA biogenesis by participating in the processing of 31-37 nt intermediates into mature piRNAs. May act in pi-bodies and piP-bodies by transferring piRNA precursors or intermediates to or between these granules.,TDRKH,TDRD2,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,TDRKH

Molecular Weight: 57 kDa/62 kDa

Gene ID: 11022

UniProt: Q9Y2W6