TP53BP2 antibody (AA 360-600)

Catalog No. ABIN6149416

The Rabbit Polyclonal anti-TP53BP2 antibody has been validated for IHC. It is suitable to detect TP53BP2 in samples from Human.

Quick Overview for TP53BP2 antibody (AA 360-600) (ABIN6149416)

Target: TP53BP2 (Tumor Protein P53 Binding Protein 2 (TP53BP2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TP53BP2 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-TP53BP2 Antibody

Binding Specificity: AA 360-600

Sequence: STMPRMPSRP ELLVKPALPD GSLVIQASEG PMKIQTLPNM RSGAASQTKG SKIHPVGPDW SPSNADLFPS QGSASVPQST GNALDQVDDG EVPLREKEKK VRPFSMFDAV DQSNAPPSFG TLRKNQSSED ILRDAQVANK NVAKVPPPVP TKPKQINLPY FGQTNQPPSD IKPDGSSQQL STVVPSMGTK PKPAGQQPRV LLSPSIPSVG QDQTLSPGSK QESPPAAAVR PFTPQPSKDT L

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 360-600 of human TP53BP2 (NP_001026855.2).

Isotype: IgG

Application Details

Application Notes: IHC,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for TP53BP2

Target: TP53BP2 (Tumor Protein P53 Binding Protein 2 (TP53BP2))

Alternative Name: TP53BP2

Background: This gene encodes a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. It is localized to the perinuclear region of the cytoplasm, and regulates apoptosis and cell growth through interactions with other regulatory molecules including members of the p53 family. Multiple transcript variants encoding different isoforms have been found for this gene.,TP53BP2,53BP2,ASPP2,BBP,P53BP2,PPP1R13A,Cancer,Tumor suppressors,p53 pathway,Cell Biology & Developmental Biology,Apoptosis,Cell Cycle,Cell cycle inhibitors,TP53BP2

Molecular Weight: 111 kDa/125 kDa/126 kDa

Gene ID: 7159

UniProt: Q13625