TP53BP2 antibody (AA 360-600)

Catalog No. ABIN7144484

Product Details anti-TP53BP2 Antibody

Target: TP53BP2 (Tumor Protein P53 Binding Protein 2 (TP53BP2))

Binding Specificity: AA 360-600

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TP53BP2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Cross-Reactivity: Human, Mouse

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Apoptosis-stimulating of p53 protein 2 protein (360-600AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:200-1:1000,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for TP53BP2

Target: TP53BP2 (Tumor Protein P53 Binding Protein 2 (TP53BP2))

Alternative Name: TP53BP2 (TP53BP2 Products)

Synonyms: 53BP2 antibody, ASPP2 antibody, BBP antibody, P53BP2 antibody, PPP1R13A antibody, TP53BP2 antibody, AI746547 antibody, Tp53bp2 antibody, X98550 antibody, Trp53bp2 antibody, wu:fa09h08 antibody, wu:fb04e08 antibody, zgc:85720 antibody, tumor protein p53 binding protein 2 antibody, tumor protein p53 binding protein 2 L homeolog antibody, tumor protein p53 binding protein, 2b antibody, transformation related protein 53 binding protein 2 antibody, tumor protein p53 binding protein, 2 antibody, tumor protein p53 binding protein, 2a antibody, TP53BP2 antibody, tp53bp2.L antibody, tp53bp2 antibody, tp53bp2b antibody, Trp53bp2 antibody, Tp53bp2 antibody, tp53bp2a antibody

Background:

Background: Regulator that plays a central role in regulation of apoptosis and cell growth via its interactions. Regulates TP53 by enhancing the DNA binding and transactivation function of TP53 on the promoters of proapoptotic genes in vivo. Inhibits the ability of APPBP1 to conjugate NEDD8 to CUL1, and thereby decreases APPBP1 ability to induce apoptosis. Impedes cell cycle progression at G2/M. Its apoptosis-stimulating activity is inhibited by its interaction with DDX42.

Aliases: 53BP2 antibody, Apoptosis stimulating of p53 protein 2 antibody, Apoptosis stimulating protein of p53 2 antibody, Apoptosis-stimulating of p53 protein 2 antibody, ASPP2 antibody, ASPP2_HUMAN antibody, BBP antibody, Bcl2 binding protein antibody, Bcl2-binding protein antibody, NY REN 51 antigen antibody, p53 binding protein 2 antibody, p53-binding protein 2 antibody, p53BP2 antibody, PPP1R13A antibody, Renal carcinoma antigen NY-REN-51 antibody, Tp53bp2 antibody, Tumor protein p53 binding protein 2 antibody, Tumor suppressor p53 binding protein 2 antibody, Tumor suppressor p53-binding protein 2 antibody

UniProt: Q13625