TRIP10 antibody (AA 246-545)

Catalog No. ABIN6149541

This Rabbit Polyclonal antibody specifically detects TRIP10 in WB and IF. It exhibits reactivity toward Human.

Quick Overview for TRIP10 antibody (AA 246-545) (ABIN6149541)

Target: TRIP10 (Thyroid Hormone Receptor Interactor 10 (TRIP10))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRIP10 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-TRIP10 Antibody

Binding Specificity: AA 246-545

Sequence: AKCLEGMKVA ANAVDPKNDS HVLIELHKSG FARPGDVEFE DFSQPMNRAP SDSSLGTPSD GRPELRGPGR SRTKRWPFGK KNKTVVTEDF SHLPPEQQRK RLQQQLEERS RELQKEVDQR EALKKMKDVY EKTPQMGDPA SLEPQIAETL SNIERLKLEV QKYEAWLAEA ESRVLSNRGD SLSRHARPPD PPASAPPDSS SNSASQDTKE SSEEPPSEES QDTPIYTEFD EDFEEEPTSP IGHCVAIYHF EGSSEGTISM AEGEDLSLME EDKGDGWTRV RRKEGGEGYV PTSYLRVTLN

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 246-545 of human TRIP10 (NP_004231.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:100

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for TRIP10

Target: TRIP10 (Thyroid Hormone Receptor Interactor 10 (TRIP10))

Alternative Name: TRIP10

Background: Required for translocation of GLUT4 to the plasma membrane in response to insulin signaling (By similarity. Required to coordinate membrane tubulation with reorganization of the actin cytoskeleton during endocytosis. Binds to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promotes membrane invagination and the formation of tubules. Also promotes CDC42-induced actin polymerization by recruiting WASL/N-WASP which in turn activates the Arp2/3 complex. Actin polymerization may promote the fission of membrane tubules to form endocytic vesicles. Required for the formation of podosomes, actin-rich adhesion structures specific to monocyte-derived cells. May be required for the lysosomal retention of FASLG/FASL.,TRIP10,CIP4,HSTP,STOT,STP,TRIP-10,Epigenetics & Nuclear Signaling,Cancer,Signal Transduction,G protein signaling,Cell Biology & Developmental Biology,Cell Cycle,Cell cycle inhibitors,Cytoskeleton,Microfilaments,Endocrine & Metabolism,Insulin Receptor Signaling Pathway,TRIP10

Molecular Weight: 39 kDa/52 kDa/62 kDa/67 kDa/68 kDa

Gene ID: 9322

UniProt: Q15642