TROVE2 antibody (AA 1-260)

Catalog No. ABIN6149562

The Rabbit Polyclonal anti-TROVE2 antibody has been validated for WB. It is suitable to detect TROVE2 in samples from Human.

Quick Overview for TROVE2 antibody (AA 1-260) (ABIN6149562)

Target: TROVE2 (TROVE Domain Family, Member 2 (TROVE2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TROVE2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TROVE2 Antibody

Binding Specificity: AA 1-260

Sequence: MEESVNQMQP LNEKQIANSQ DGYVWQVTDM NRLHRFLCFG SEGGTYYIKE QKLGLENAEA LIRLIEDGRG CEVIQEIKSF SQEGRTTKQE PMLFALAICS QCSDISTKQA AFKAVSEVCR IPTHLFTFIQ FKKDLKESMK CGMWGRALRK AIADWYNEKG GMALALAVTK YKQRNGWSHK DLLRLSHLKP SSEGLAIVTK YITKGWKEVH ELYKEKALSV ETEKLLKYLE AVEKVKRTRD ELEVIHLIEE HRLVREHLLT

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human TROVE2 (NP_004591.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for TROVE2

Target: TROVE2 (TROVE Domain Family, Member 2 (TROVE2))

Alternative Name: TROVE2

Background: RNA-binding protein that binds to misfolded non-coding RNAs, pre-5S rRNA, and several small cytoplasmic RNA molecules known as Y RNAs. May stabilize some of these RNAs and protect them from degradation. Binds to endogenous Alu retroelements which are induced by type I interferon and stimulate porinflammaotry cytokine secretion. Regulates the expression of Alu retroelements as well as inflammatory genes.,TROVE2,RO60,RORNP,SSA2,Epigenetics & Nuclear Signaling,Immunology & Inflammation,TROVE2

Molecular Weight: 23 kDa/58 kDa/59 kDa/60 kDa

Gene ID: 6738

UniProt: P10155