TYR antibody (AA 20-340)

Catalog No. ABIN6149746

The Rabbit Polyclonal anti-TYR antibody has been validated for WB. It is suitable to detect TYR in samples from Human.

Quick Overview for TYR antibody (AA 20-340) (ABIN6149746)

Target: TYR (Tyrosinase (TYR))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TYR antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TYR Antibody

Binding Specificity: AA 20-340

Sequence: FPRACVSSKN LMEKECCPPW SGDRSPCGQL SGRGSCQNIL LSNAPLGPQF PFTGVDDRES WPSVFYNRTC QCSGNFMGFN CGNCKFGFWG PNCTERRLLV RRNIFDLSAP EKDKFFAYLT LAKHTISSDY VIPIGTYGQM KNGSTPMFND INIYDLFVWM HYYVSMDALL GGSEIWRDID FAHEAPAFLP WHRLFLLRWE QEIQKLTGDE NFTIPYWDWR DAEKCDICTD EYMGGQHPTN PNLLSPASFF SSWQIVCSRL EEYNSHQSLC NGTPEGPLRR NPGNHDKSRT PRLPSSADVE FCLSLTQYES GSMDKAANFS F

Cross-Reactivity: Human, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 20-340 of human TYR (NP_000363.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for TYR

Target: TYR (Tyrosinase (TYR))

Alternative Name: TYR

Background: The enzyme encoded by this gene catalyzes the first 2 steps, and at least 1 subsequent step, in the conversion of tyrosine to melanin. The enzyme has both tyrosine hydroxylase and dopa oxidase catalytic activities, and requires copper for function. Mutations in this gene result in oculocutaneous albinism, and nonpathologic polymorphisms result in skin pigmentation variation. The human genome contains a pseudogene similar to the 3' half of this gene.,TYR,ATN,CMM8,OCA1,OCA1A,OCAIA,SHEP3,Signal Transduction,Endocrine & Metabolism,Amino acid metabolism,TYR

Molecular Weight: 42 kDa/60 kDa

Gene ID: 7299

UniProt: P14679