PLIN3 antibody (Internal Region)

Catalog No. ABIN614987

The Goat Polyclonal anti-PLIN3 antibody is suitable to detect PLIN3 in samples from Mouse and Rat. It has been validated for WB, IHC (p) and EIA.

Quick Overview for PLIN3 antibody (Internal Region) (ABIN614987)

Target: PLIN3 (Perilipin 3 (PLIN3))

Reactivity: Mouse, Rat

Host: Goat

Clonality: Polyclonal

Conjugate: This PLIN3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-PLIN3 Antibody

Binding Specificity: Internal Region

Sequence: C-NQKTPQDAEK DPAK

Specificity: This antibody reacts to Mannose-6-phosphate Receptor Binding Protein 1 (M6PRBP1).

Cross-Reactivity (Details): Species reactivity (expected):Rat.
Species reactivity (tested):Mouse.

Purification: Immunoaffinity Chromatography

Immunogen: Synthetic peptide from an internal region of mouse M6PRBP1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0,5 mg/mL

Buffer: Tris saline buffer, pH 7.3 containing 0.5 % BSA as stabilizer and 0.02 % sodium azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Target Details for PLIN3

Target: PLIN3 (Perilipin 3 (PLIN3))

Alternative Name: TIP47 / M6PRBP1

Background: Mannose 6-phosphate receptors (MPRs) deliver lysosomal hydrolase from the Golgi to endosomes and then return to the Golgi complex. M6PRBP1 interacts with the cytoplasmic domains of both cation-independent and cation-dependent MPRs, and is required for endosome-to-Golgi transport. This protein also binds directly to the GTPase RAB9 (RAB9A), a member of the RAS oncogene family. The interaction with RAB9 has been shown to increase the affinity of this protein for its cargo.Synonyms: 47 kDa mannose 6-phosphate receptor-binding protein, Cargo selection protein TIP47, Mannose-6-phosphate receptor-binding protein 1, Placental protein 17

Gene ID: 66905

NCBI Accession: NP_080112

UniProt: Q9DBG5