WNT3 antibody (AA 166-355)

Catalog No. ABIN6150242

The Rabbit Polyclonal anti-WNT3 antibody has been validated for WB. It is suitable to detect WNT3 in samples from Human.

Quick Overview for WNT3 antibody (AA 166-355) (ABIN6150242)

Target: WNT3 (Wingless-Type MMTV Integration Site Family, Member 3 (WNT3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WNT3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-WNT3 Antibody

Binding Specificity: AA 166-355

Sequence: VLVSREFADA RENRPDARSA MNKHNNEAGR TTILDHMHLK CKCHGLSGSC EVKTCWWAQP DFRAIGDFLK DKYDSASEMV VEKHRESRGW VETLRAKYSL FKPPTERDLV YYENSPNFCE PNPETGSFGT RDRTCNVTSH GIDGCDLLCC GRGHNTRTEK RKEKCHCIFH WCCYVSCQEC IRIYDVHTCK

Cross-Reactivity: Human

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 166-355 of human WNT3 (NP_110380.1).

Isotype: IgG

Application Details

Application Notes: WB,1:200 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for WNT3

Target: WNT3 (Wingless-Type MMTV Integration Site Family, Member 3 (WNT3))

Alternative Name: WNT3

Background: The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 98 % amino acid identity to mouse Wnt3 protein, and 84 % to human WNT3A protein, another WNT gene product. The mouse studies show the requirement of Wnt3 in primary axis formation in the mouse. Studies of the gene expression suggest that this gene may play a key role in some cases of human breast, rectal, lung, and gastric cancer through activation of the WNT-beta-catenin-TCF signaling pathway. This gene is clustered with WNT15, another family member, in the chromosome 17q21 region.,WNT3,INT4,TETAMS,Epigenetics & Nuclear Signaling,Translation Control,Regulation of eIF4 and p70 S6 Kinase,Signal Transduction,mTOR Signaling Pathway,Cell Biology & Developmental Biology,Wnt/β-Catenin Signaling Pathway,ESC Pluripotency and Differentiation,Neuroscience,Stem Cells,WNT3

Molecular Weight: 39 kDa

Gene ID: 7473

UniProt: P56703

Pathways: WNT Signaling, Regulation of Cell Size