TTR antibody

Catalog No. ABIN615282

This anti-TTR antibody is a Goat Polyclonal antibody detecting TTR in IHC (p) and EIA. Suitable for Human.

Quick Overview for TTR antibody (ABIN615282)

Target: TTR (Transthyretin (TTR))

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This TTR antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-TTR Antibody

Specificity: This antibody reacts to Transthyretin (TTR).

Purification: Immunoaffinity Chromatography

Immunogen: TTR antibody was raised against purified human Prealbumin

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: PBS, pH 7.2 containing 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for TTR

Target: TTR (Transthyretin (TTR))

Alternative Name: Transthyretin / Prealbumin

Background: Prealbumin, also known as transethrytin (TTR) is a carrier protein, it transports thyroid hormones in the plasma and cerebrospinal fluid, and also transports retinol (vitamin A) in the plasma. The protein consists of a tetramer of identical subunits. More than 80 different mutations in this gene have been reported, most mutations are related to amyloid deposition, affecting predominantly peripheral nerve and/or the heart, and a small portion of the gene mutations is non-amyloidogenic. The diseases caused by mutations include amyloidotic polyneuropathy, euthyroid hyperthyroxinaemia, amyloidotic vitreous opacities, cardiomyopathy, oculoleptomeningeal amyloidosis, meningocerebrovascular amyloidosis, carpal tunnel syndrome, etc.Synonyms: ATTR, PALP, TBPA, TTR

Gene ID: 7276

NCBI Accession: NP_000362

UniProt: P02766

Pathways: Hormone Transport