ASS1 antibody (Internal Region)

Catalog No. ABIN615430

This Goat Polyclonal antibody specifically detects ASS1 in WB, IP, IHC (p) and EIA. It exhibits reactivity toward Human.

Quick Overview for ASS1 antibody (Internal Region) (ABIN615430)

Target: ASS1 (Argininosuccinate Synthase 1 (ASS1))

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This ASS1 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-ASS1 Antibody

Binding Specificity: Internal Region

Sequence: C-ENPKNQAPPG LYTKTQD

Specificity: This antibody detects ASS1 (Internal).

Cross-Reactivity (Details): Species reactivity (expected):Dog, Mouse, RatSpecies reactivity (tested):Human

Purification: Immunoaffinity chromatography

Immunogen: Synthetic peptide from an internal region of human ASS1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Tris saline buffer, pH 7.3, 0.5 % BSA, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Target Details for ASS1

Target: ASS1 (Argininosuccinate Synthase 1 (ASS1))

Alternative Name: ASS1

Background: Arginosuccinate synthetase catalyzes the penultimate step of the arginine biosynthetic pathway. There are approximately 10 to 14 ASS pseudogenes scattered across the human genome, the ASS gene located on chromosome 9 appears to be the only functional gene for argininosuccinate synthetase. The ASS primary transcript is subject to alternative splicing in the 5' non-coding region, a splice variant lacking exon 2 occurs in liver and fibroblast cells. Mutations in the chromosome 9 copy of ASS cause citrullinemia.Synonyms: Argininosuccinate synthase, Citrulline-aspartate ligase

Gene ID: 445

NCBI Accession: NP_000041

UniProt: P00966

Pathways: Response to Growth Hormone Stimulus, Cellular Response to Molecule of Bacterial Origin