EBV EA p55,p50 antibody (CF®405S)
Quick Overview for EBV EA p55,p50 antibody (CF®405S) (ABIN6154517)
Target
Reactivity
Host
Clonality
Conjugate
Application
Clone
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Purpose
- Mouse Monoclonal anti-p55,50 EBV Early Antigen (1108-1), CF405S Conjugate
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Characteristics
- Epstein-Barr virus (EBV), also designated human herpesvirus 4 (HHV-4), is a member of the herpesvirus family and is one of the most common human viruses. EBV infects B cells and, though often asymptomatic, it can cause infectious mononucleosis, a disease characterized by fatigue, fever, sore throat and muscle soreness. The EBV-induced early antigens (Ea) are among several antigen complexes that have been identified in EBV-infected cells. The Ea complex is composed of diffuse (Ea-D) and restricted (Ea-R) components. The activity of Ea-D is suppressed during latent infection. BMRF1, the gene that encodes for Ea-D, is closely associated with the gene encoding for EBV DNA polymerase, and Ea-D is essential for the activity of this polymerase. Ea-D forms a complex with EBV DNase and, together, they may play a role in viral replication. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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Isotype
- IgG1 kappa
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Application Notes
- Immunofluorescence 0.5-1 μg/mLOptimal dilution for a specific application should be determined by user
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Comment
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EBV-infected cells or tissues
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 100 μg/mL
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Buffer
- PBS/0.1 % BSA/0.05 % azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Protect from light
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- EBV EA p55,p50 (Epstein-Barr Virus Early Antigen p55,p50 (EBV EA p55,p50))
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Alternative Name
- p55,50 Early Antigen
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Target Type
- Viral Protein
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Background
- EBNA1, EBV nuclear antigen 1, Epstein Barr nuclear antigen 1, Human Herpesvirus 4 (HHV4)
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Molecular Weight
- 50/55 kDa doublet
Target
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