PDGFB antibody (C-Term)

Catalog No. ABIN615518

The Goat Polyclonal anti-PDGFB antibody has been validated for IHC (p). It is suitable to detect PDGFB in samples from Human.

Quick Overview for PDGFB antibody (C-Term) (ABIN615518)

Target: PDGFB (Platelet Derived Growth Factor Subunit B (PDGFB))

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This PDGFB antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-PDGFB Antibody

Binding Specificity: C-Term

Specificity: This antibody detects PDGFB (C-term).

Cross-Reactivity (Details): Species reactivity (expected):Bovine, Canine, Mouse, Rat and Sheep.
Species reactivity (tested):Human.

Purification: Immunoaffinity Chromatography

Immunogen: KLH conjugated synthetic peptide from C-Terminus of human PDGFB

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH 7.3 containing 0.02 % sodium azide as preservative and 0.5 % BSA as stabilizer

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for PDGFB

Target: PDGFB (Platelet Derived Growth Factor Subunit B (PDGFB))

Alternative Name: PDGFB

Background: PDGF-B is the major polypeptide mitogen in serum for cells of mesenchymal origin, it promotes cellular proliferation and inhibits apoptosis.Synonyms: Becaplermin, PDGF B, PDGF beta, PDGF subunit B, PDGF-2, PDGF-B, PDGF2, Platelet-derived growth factor B chain, Platelet-derived growth factor beta, Platelet-derived growth factor subunit B, SIS, c-Sis

Gene ID: 5155

NCBI Accession: NP_002599

UniProt: P01127

Pathways: RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Carbohydrate Metabolic Process, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling