FPR1 antibody

Catalog No. ABIN615853

This Rabbit Polyclonal antibody specifically detects FPR1 in WB, IF, IHC (p) and EIA. It exhibits reactivity toward Human.

Quick Overview for FPR1 antibody (ABIN615853)

Target: FPR1 (Formyl Peptide Receptor 1 (FPR1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FPR1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-FPR1 Antibody

Specificity: FPR1 Antibody detects endogenous levels of total FPR1 protein.

Purification: Immunoaffinity Chromatography

Immunogen: Synthetic peptide - KLH conjugated, Synthetic peptide Genename: FPR1

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1,0 mg/mL

Buffer: PBS (without Mg2+, Ca2+), pH 7.4 containing 150 mM sodium chloride, 0.02 % sodium azide as preservative and 50 % glycerol as stabilizer

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Target Details for FPR1

Target: FPR1 (Formyl Peptide Receptor 1 (FPR1))

Alternative Name: fMLP Receptor

Background: Formyl peptide receptor 1, a Chemoattractant Receptor, mediates chemotaxis, degranulation, and superoxide production, as part of the inflammatory response. Bacterial N-formylmethionyl peptides and Annexin A1, specific ligands for FPR1, attract polymorphonuclear neutrophils to sites of infection. FPR receptors promote the phosphorylation and downregulation of CCR5, which has been shown to inhibit HIV infection. Therefore, ligands for an FPR receptor may be able to inhibit HIV infection.Synonyms: FPR1, N-formyl peptide receptor, N-formylpeptide chemoattractant receptor, fMet-Leu-Phe receptor

Gene ID: 2357

NCBI Accession: NP_001180235

UniProt: P21462