ACTN3 antibody (N-Term)

Catalog No. ABIN615863

The Rabbit Polyclonal anti-ACTN3 antibody has been validated for WB, IHC (p) and EIA. It is suitable to detect ACTN3 in samples from Human, Mouse and Rat.

Quick Overview for ACTN3 antibody (N-Term) (ABIN615863)

Target: ACTN3 (Actinin, alpha 3 (ACTN3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ACTN3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-ACTN3 Antibody

Binding Specificity: N-Term

Specificity: This antibody reacts to the N-term of Alpha-actinin 3, Skeletal Muscle Isoform (ACTN3).

Purification: Immunoaffinity Chromatography

Immunogen: ACTN3 antibody was raised against synthetic peptide - KLH conjugated Genename: ACTN3

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1,0 mg/mL

Buffer: PBS (without Mg2+, Ca2+), pH 7.4 containing 150 mM sodium chloride, 0.02 % sodium azide as preservative and 50 % glycerol as stabilizer

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Target Details for ACTN3

Target: ACTN3 (Actinin, alpha 3 (ACTN3))

Alternative Name: alpha-Actinin-3 / ACTN3

Background: Alpha-actinin is an actin-binding protein with multiple roles in different cell types. ACTN3 expression is limited to skeletal muscle. It is localized to the Z-disc and analogous dense bodies, where it helps to anchor the myofibrillar actin filaments.Synonyms: Alpha actinin skeletal muscle isoform 3, F-actin cross-linking protein

Gene ID: 89

NCBI Accession: NP_001095

UniProt: Q08043

Pathways: Cell-Cell Junction Organization