FSHR antibody (Internal Region)
Quick Overview for FSHR antibody (Internal Region) (ABIN615866)
Target
See all FSHR AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- Internal Region
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Specificity
- This antibody detects endogenous levels of total FSHR protein.
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Purification
- Immunoaffinity Chromatography
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Immunogen
- Synthetic peptide from Human FSHR. Epitope: Internal Genename: FSHR
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Isotype
- IgG
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- PBS (without Mg2+, Ca2+), pH 7.4 containing 150 mM Sodium Chloride, 0.02 % Sodium Azide and 50 % Glycerol
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freezing and thawing.
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Storage
- -20 °C
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- FSHR (Follicle Stimulating Hormone Receptor (FSHR))
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Alternative Name
- FSH Receptor
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Background
- FSHR, a Glycoprotein Hormone Receptor, is required for normal ovarian development and follicle maturation in females. When activated, it stimulates ovarian follicular growth and production of estrogens, initiating a normal menstrual cycle. In males, FSHR is required for the initiation of spermatogenesis and normal sperm production. Two isoforms are produced by alternative splicing.Synonyms: FSH-R, Follicle-stimulating hormone receptor, Follitropin receptor, LGR1
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Gene ID
- 2492
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NCBI Accession
- NP_000136
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UniProt
- P23945
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Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Hormone Metabolic Process, Platelet-derived growth Factor Receptor Signaling
Target
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