FSHR antibody (Internal Region)

Catalog No. ABIN615866

The Rabbit Polyclonal anti-FSHR antibody is suitable to detect FSHR in samples from Human. It has been validated for IF, IHC (p) and EIA.

Quick Overview for FSHR antibody (Internal Region) (ABIN615866)

Target: FSHR (Follicle Stimulating Hormone Receptor (FSHR))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FSHR antibody is un-conjugated

Application: Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-FSHR Antibody

Binding Specificity: Internal Region

Specificity: This antibody detects endogenous levels of total FSHR protein.

Purification: Immunoaffinity Chromatography

Immunogen: Synthetic peptide from Human FSHR. Epitope: Internal Genename: FSHR

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS (without Mg2+, Ca2+), pH 7.4 containing 150 mM Sodium Chloride, 0.02 % Sodium Azide and 50 % Glycerol

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Target Details for FSHR

Target: FSHR (Follicle Stimulating Hormone Receptor (FSHR))

Alternative Name: FSH Receptor

Background: FSHR, a Glycoprotein Hormone Receptor, is required for normal ovarian development and follicle maturation in females. When activated, it stimulates ovarian follicular growth and production of estrogens, initiating a normal menstrual cycle. In males, FSHR is required for the initiation of spermatogenesis and normal sperm production. Two isoforms are produced by alternative splicing.Synonyms: FSH-R, Follicle-stimulating hormone receptor, Follitropin receptor, LGR1

Gene ID: 2492

NCBI Accession: NP_000136

UniProt: P23945

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Hormone Metabolic Process, Platelet-derived growth Factor Receptor Signaling