SH3GL1 antibody (Internal Region)

Catalog No. ABIN615965

The Goat Polyclonal anti-SH3GL1 antibody is suitable to detect SH3GL1 in samples from Human, Dog and Cow. It has been validated for WB and EIA.

Quick Overview for SH3GL1 antibody (Internal Region) (ABIN615965)

Target: SH3GL1 (SH3-Domain GRB2-Like 1 (SH3GL1))

Reactivity: Human, Dog, Cow

Host: Goat

Clonality: Polyclonal

Conjugate: This SH3GL1 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-SH3GL1 Antibody

Binding Specificity: Internal Region

Sequence: C-EPFDLGEPEQ SN

Specificity: Recognizes Endophilin-A2

Cross-Reactivity (Details): Species reactivity (expected):Canine (Dog), Cow.
Species reactivity (tested):Human.

Purification: Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide.

Immunogen: Peptide with sequence from the internal region of the protein sequence according to NP_003016.1. Genename: SH3GL1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for SH3GL1

Target: SH3GL1 (SH3-Domain GRB2-Like 1 (SH3GL1))

Alternative Name: Endophilin-A2

Background: This gene encodes a member of the endophilin family of Src homology 3 domain-containing proteins. The encoded protein is involved in endocytosis and may also play a role in the cell cycle. Overexpression of this gene may play a role in leukemogenesis, and the encoded protein has been implicated in acute myeloid leukemia as a fusion partner of the myeloid-lymphoid leukemia protein. Pseudogenes of this gene are located on the long arm of chromosomes 11 and 17. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.Synonyms: CNSA1, Endophilin-2, Extra eleven-nineteen leukemia fusion gene protein, SH3 domain protein 2B, SH3 domain-containing GRB2-like protein 1, SH3D2B, SH3GL1

Gene ID: 6455

NCBI Accession: NP_003016

UniProt: Q99961