RBP1 antibody (CF®594)
Quick Overview for RBP1 antibody (CF®594) (ABIN6172726)
Target
See all RBP1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Purpose
- Mouse Monoclonal anti-Retinol Binding Protein 1 (RBP/872), CF594 Conjugate
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Characteristics
- This antibody recognizes a protein of 21 kDa-25 kDa, identified as retinol binding protein-1 (RBP1). This protein belongs to the lipocalin family and is the specific carrier for retinol (vitamin A alcohol) in the blood. It delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin, which prevents its loss by filtration through the kidney glomeruli. A deficiency of vitamin A blocks secretion of the binding protein post-transnationally and results in defective delivery and supply to the epidermal cells. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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Immunogen
- Recombinant human retinol binding protein-1 (RBP1)
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Isotype
- IgG1 kappa
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Application Notes
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Immunohistology formalin-fixed 1-2 μg/mL
- Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes
- Immunofluorescence 1-2 μg/mL
- Optimal dilution for a specific application should be determined by user
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Comment
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Hepatic or ovarian carcinoma
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 100 μg/mL
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Buffer
- PBS/0.1 % BSA/0.05 % azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Protect from light
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- RBP1 (Retinol Binding Protein 1, Cellular (RBP1))
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Alternative Name
- Retinol Binding Protein 1
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Molecular Weight
- 21-25 kDa
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Gene ID
- 5947, 5948, 5950
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UniProt
- P02753
Target
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