The Rabbit Polyclonal anti-Phosducin antibody (ABIN619539) specifically detects Phosducin in WB.
The antibody is reactive with Arabidopsis thaliana, Oryza sativa and Zymomonas mobilis samples.
PDC
Reactivity: Human
WB, ELISA
Host: Rabbit
Polyclonal
HRP
Application Notes
1 : 10 000 (WB)
Restrictions
For Research Use only
Format
Lyophilized
Reconstitution
For reconstitution add 100 μL of sterile water
Buffer
Serum
Handling Advice
Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube
Storage
-20 °C
Storage Comment
Store lyophilized/reconstituted at -20°C, once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.
Target
Phosducin (PDC)
Alternative Name
PDC
Background
Pyruvate decarboxylase (PDC) is a homotetrameric enzyme (E.C.4.1.1.1) that catalyses the decarboxylation of pyruvic acid to acetaldehyde carbon dioxide in the cytoplasm. It is also called 2-oxo-acid carboxylase, and pyruvic decarboxylase. In anaerobic conditions, this enzyme is part of the fermentation process that occurs in yeast, especially the Saccharomyces genus, to produce ethanol by fermentation. Pyruvate decarboxylase starts this process by converting pyruvate into acetaldehyde and carbon dioxide. Pyruvate decarboxylase depends on cofactors thiamine pyrophosphate (TPP) and magnesium. This enzyme should not be mistaken for the unrelated enzyme pyruvate dehydrogenase, an oxidoreductase (EC 1.2.4.1), that catalyzes the oxidative decarboxylation of pyruvate to acetyl-CoA.