Histone H2A antibody (C-Term)

Catalog No. ABIN6141563

This anti-Histone H2A antibody is a Rabbit Polyclonal antibody detecting Histone H2A in WB, IHC and IF. Suitable for Human. This Primary Antibody has been cited in 1 publication.

Quick Overview for Histone H2A antibody (C-Term) (ABIN6141563)

Target: Histone H2A

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Histone H2A antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-Histone H2A Antibody

Binding Specificity: C-Term

Sequence: VYLAAVLEYL TAEILELAGN AARDNKKTRI IPRHLQLAIR NDEELNKLLG GVTIAQGGVL PNIQAVLLPK KTSATVGPKA PSGGKKATQA SQEY

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 50 to the C-terminus of human Histone H2AX (NP_002096.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:1000,IHC,1:100 - 1:200,IF,1:50 - 1:200

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

References for anti-Histone H2A antibody (ABIN6141563)

Diaz, Engle, Tice, Melis, Montenegro, Rodriguez-Canales, Hanson, Emmert-Buck, Bock, Moore, Zamboni, Govindarajan, Kleiner, Farci: "Molecular Signature and Mechanisms of Hepatitis D Virus-Associated Hepatocellular Carcinoma." in: Molecular cancer research : MCR, Vol. 16, Issue 9, pp. 1406-1419, (2018) (PubMed).

Target Details for Histone H2A

Target: Histone H2A

Background: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-independent histone that is a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif.,H2A.X,H2A/X,H2AX,Histone H2AX,H2AFX,histone H2AX,gamma H2A.X,γH2AX,Epigenetics & Nuclear Signaling,Histones,DNA Damage & Repair,Histone H2A

Molecular Weight: 15 kDa

Gene ID: 3014

UniProt: P16104