This anti-PPP1CA antibody is a Rabbit Polyclonal antibody detecting PPP1CA in WB and IHC. Suitable for Human, Mouse and Rat. This Primary Antibody has been cited in 1 publication.
Type 1 protein phosphatase (PP1), a serine/threonine phosphatase, is highly conserved in eukaryotic cells. Four isoforms of PP1 have been characterized: PP1alpha, PP1delta, PP1gamma1 and PP1gamma2. Involvement in cell cycle regulation is one of the biological functions of PP1. It has been illustrated that PP1 dephosphorylates Rb and cdc25 during mitosis. A cell cycle-dependent phosphorylation at Thr320 of PP1alpha by cdc2 kinase inhibits PP1alpha activity. Synonyms: PPP1CA, MGC15877, MGC1674, PP-1A, PP1alpha, PPP1A