SUZ12 antibody (AA 375-408)

Catalog No. ABIN6242142

The Rabbit Polyclonal anti-SUZ12 antibody is suitable to detect SUZ12 in samples from Human and Mouse. It has been validated for WB.

Quick Overview for SUZ12 antibody (AA 375-408) (ABIN6242142)

Target: SUZ12 (SUZ12 Polycomb Repressive Complex 2 Subunit (SUZ12))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SUZ12 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB51415

Product Details anti-SUZ12 Antibody

Binding Specificity: AA 375-408

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This SUZ12 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 375-408 amino acids from the Central region of human SUZ12.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

Target Details for SUZ12

Target: SUZ12 (SUZ12 Polycomb Repressive Complex 2 Subunit (SUZ12))

Alternative Name: SUZ12

Background: Polycomb group (PcG) protein. Component of the PRC2/EED- EZH2 complex, which methylates 'Lys-9' (H3K9me) and 'Lys-27' (H3K27me) of histone H3, leading to transcriptional repression of the affected target gene. The PRC2/EED-EZH2 complex may also serve as a recruiting platform for DNA methyltransferases, thereby linking two epigenetic repression systems. Genes repressed by the PRC2/EED-EZH2 complex include HOXC8, HOXA9, MYT1 and CDKN2A.

Molecular Weight: 83055

UniProt: Q15022