BANP antibody (AA 30-390)

Catalog No. ABIN6242199

The Mouse Monoclonal anti-BANP antibody has been validated for WB and IHC (p). It is suitable to detect BANP in samples from Human.

Quick Overview for BANP antibody (AA 30-390) (ABIN6242199)

Target: BANP (Protein BANP (BANP))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This BANP antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 1524CT337-6-32

Product Details anti-BANP Antibody

Binding Specificity: AA 30-390

Purification: This antibody is purified through a protein G column, followed by dialysis against PBS.

Immunogen: This BANP antibody is generated from a mouse immunized with a recombinant protein between 30-390 amino acids from human BANP.

Isotype: IgG1 kappa

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:25

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

Target Details for BANP

Target: BANP (Protein BANP (BANP))

Alternative Name: BANP

Background: Controls V(D)J recombination during T-cell development by repressing T-cell receptor (TCR) beta enhancer function. Binds to scaffold/matrix attachment region beta (S/MARbeta), an ATC-rich DNA sequence located upstream of the TCR beta enhancer. Represses cyclin D1 transcription by recruiting HDAC1 to its promoter, thereby diminishing H3K9ac, H3S10ph and H4K8ac levels. Promotes TP53 'Ser-15' phosphorylation and nuclear accumulation, which causes cell cycle arrest (By similarity).

Molecular Weight: 56494

UniProt: Q8N9N5