For best experience we recommend to activate Javascript in your browser.

EGFR antibody (AA 847-876)

Name: EGFR antibody (AA 847-876)
SKU: ABIN6242299
Price: 451 USD
Availability: InStock

EGFR Reactivity: Human WB Host: Rabbit Polyclonal RB10970 unconjugated

Western blot analysis of EGFR (arrow) using rabbit polyclonal EGFR Antibody h. (EGFR antibody (AA 847-876))

All lanes : Anti-EGFR Antibody at 1:1000 dilution Lane 1: A431 whole cell lysate Lane 2: MDA-MB-231 whole cell lysate Lysates/proteins at 20 μg per lane. (EGFR antibody (AA 847-876))

2 images

Catalog No. ABIN6242299

Datasheet as PDF

Target See all EGFR Antibodies

EGFR (Epidermal Growth Factor Receptor (EGFR))
Binding Specificity
39

38

31

31

30

27

27

26

25

22

19

18

16

16

16

15

15

15

11

11

10

9

9

9

8

8

7

6

5

5

5

5

5

4

4

4

4

4

4

4

3

3

3

3

3

3

3

3

3

3
AA 847-876
Reactivity
750

296

283

25

25

24

19

14

8

3

2

2

1

1

1

1

1

1
Human
Host
579

168

14

13

5

4

1

1
Rabbit
Compatible Secondaries
Clonality
541

239

2
Polyclonal
Conjugate
412

58

29

22

19

17

16

16

16

16

16

11

10

10

10

10

10

10

10

10

10

8

8

5

4

4

4

4

4

1

1

1

1

1

1
This EGFR antibody is un-conjugated
Application
535

252

149

145

127

102

98

93

82

48

37

34

34

18

11

8

6

5

4

4

3

3

3

3

3

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1
Western Blotting (WB)

Predicted Reactivity

M

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen

This EGFR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 847-876 amino acids from human EGFR.

Clone

RB10970

Isotype

Ig Fraction

Top Product

Discover our top product EGFR Primary Antibody
anti-Epidermal Growth Factor Receptor (EGFR) (AA 693-893) antibody
EGFR Reactivity: Human WB, ELISA, IHC, FACS Host: Mouse Monoclonal 7A6F12 unconjugated

anti-Epidermal Growth Factor Receptor (EGFR) (AA 888-1210) antibody
EGFR Reactivity: Human WB, IHC, IP, ICC Host: Mouse Monoclonal C4 unconjugated

anti-Epidermal Growth Factor Receptor (EGFR) (pSer1026) antibody
EGFR Reactivity: Human, Mouse, Rat WB, ELISA, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated

anti-Epidermal Growth Factor Receptor (EGFR) (pSer1071) antibody
EGFR Reactivity: Human, Mouse, Rat WB, ELISA, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated

anti-Epidermal Growth Factor Receptor (EGFR) (pSer695) antibody
EGFR Reactivity: Human, Mouse, Rat WB, ELISA, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated

anti-Epidermal Growth Factor Receptor (EGFR) (AA 1163-1191), (C-Term) antibody
EGFR Reactivity: Human WB, IHC (p) Host: Mouse Monoclonal 688CT33-1-3 unconjugated

anti-Epidermal Growth Factor Receptor (EGFR) (C-Term) antibody
EGFR Reactivity: Human, Mouse, Rat, Pig, Monkey, Cow, Chicken, Dog, Horse, Rabbit, Guinea Pig, Avian, Cat, Donkey, Goat, Hamster, Sheep WB Host: Goat Polyclonal unconjugated

anti-Epidermal Growth Factor Receptor (EGFR) (AA 693-893) antibody
EGFR Reactivity: Human WB, ELISA, FACS Host: Mouse Monoclonal 5E10D3 unconjugated

anti-Epidermal Growth Factor Receptor (EGFR) (AA 1021-1210) antibody
EGFR Reactivity: Human WB, IF, IP Host: Rabbit Polyclonal unconjugated

anti-Epidermal Growth Factor Receptor (EGFR) (C-Term) antibody
EGFR Reactivity: Human, Rat WB, ELISA, IHC, IP Host: Rabbit Polyclonal unconjugated

Application Notes

WB: 1:1000. WB: 1:1000

Restrictions

For Research Use only
Format

Liquid

Buffer

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative

Sodium azide

Precaution of Use

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage

4 °C,-20 °C

Expiry Date

6 months
Target

EGFR (Epidermal Growth Factor Receptor (EGFR))

Alternative Name

EGFR (EGFR Products)

Background

EGFR is a transmembrane glycoprotein that is a member of a family of protein tyrosine kinases crucial in maintaining a normal balance in cell growth and development. A prototype member of the type 1 receptor tyrosine kinases, EGFR is encoded by the cellular oncogene cerbB1. EGFR has an extracellular ligand binding domain, a single transmembrane region, and cytoplasmic domain which is composed of a tyrosine kinase domain and a carboxy terminal domain. The carboxy terminal domain contains at least four tyrosine autophosphorylation sites. Increased production or activation of EGFR has been associated with poor prognosis in a variety of tumors. EGFR overexpression is observed in tumors of the head and neck, brain, bladder, stomach, breast, lung, endometrium, cervix, vulva, ovary, esophagus, stomach and in squamous cell carcinoma.

Molecular Weight

134277

NCBI Accession

NP_005219, NP_958439, NP_958440, NP_958441

UniProt

P00533

Pathways

NF-kappaB Signaling, RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Stem Cell Maintenance, Hepatitis C, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, EGFR Downregulation, S100 Proteins