XRN1 antibody (C-Term)

Catalog No. ABIN6242394

Product Details anti-XRN1 Antibody

Target: XRN1 (5'-3' Exoribonuclease 1 (XRN1))

Binding Specificity: AA 1389-1423, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This XRN1 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This XRN1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 1389-1423 amino acids from the C-terminal region of human XRN1.

Clone: RB49366

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

Target Details for XRN1

Target: XRN1 (5'-3' Exoribonuclease 1 (XRN1))

Alternative Name: XRN1 (XRN1 Products)

Background: Major 5'-3' exoribonuclease involved in mRNA decay. Required for the 5'-3'-processing of the G4 tetraplex-containing DNA and RNA substrates. The kinetic of hydrolysis is faster for G4 RNA tetraplex than for G4 DNA tetraplex and monomeric RNA tetraplex. Binds to RNA and DNA (By similarity). Plays a role in replication-dependent histone mRNA degradation. May act as a tumor suppressor protein in osteogenic sarcoma (OGS).

Molecular Weight: 194107

UniProt: Q8IZH2