Aconitase 1 antibody (AA 354-388)

Catalog No. ABIN6242413

Product Details anti-Aconitase 1 Antibody

Target: Aconitase 1 (ACO1)

Binding Specificity: AA 354-388

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Aconitase 1 antibody is un-conjugated

Application: Western Blotting (WB)

Predicted Reactivity: B, C, Rb

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This ACO1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 354-388 amino acids from the Central region of human ACO1.

Clone: RB54996

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

Target Details for Aconitase 1

Target: Aconitase 1 (ACO1)

Alternative Name: ACO1 (ACO1 Products)

Background: Iron sensor. Binds a 4Fe-4S cluster and functions as aconitase when cellular iron levels are high. Functions as mRNA binding protein that regulates uptake, sequestration and utilization of iron when cellular iron levels are low. Binds to iron-responsive elements (IRES) in target mRNA species when iron levels are low. Binding of a 4Fe-4S cluster precludes RNA binding.

Molecular Weight: 98399

UniProt: P21399

Pathways: Transition Metal Ion Homeostasis