Nicastrin antibody (AA 99-133)
NCSTN
Reactivity: Human, Rat
WB
Host: Rabbit
Polyclonal
RB53031
unconjugated
-
- Target See all Nicastrin (NCSTN) Antibodies
- Nicastrin (NCSTN)
- Binding Specificity
- AA 99-133
- Reactivity
- Human, Rat
- Host
- Rabbit
- Clonality
- Polyclonal
- Application
- Western Blotting (WB)
- Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogen
- This NCSTN antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 99-133 amino acids from human NCSTN.
- Clone
- RB53031
- Isotype
- Ig Fraction
-
- Application Notes
- WB: 1:2000. WB: 1:8000
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Expiry Date
- 6 months
-
- Target
- Nicastrin (NCSTN)
- Alternative Name
- NCSTN
- Background
- Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta- amyloid precursor protein). It probably represents a stabilizing cofactor required for the assembly of the gamma-secretase complex.
- Molecular Weight
- 78411
- UniProt
- Q92542
- Pathways
- Notch Signaling, Neurotrophin Signaling Pathway
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