PACSIN2 antibody (AA 250-486)

Catalog No. ABIN6242514

Product Details anti-PACSIN2 Antibody

Target: PACSIN2 (Protein Kinase C and Casein Kinase Substrate in Neurons 2 (PACSIN2))

Binding Specificity: AA 250-486

Reactivity: Human, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This PACSIN2 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein G column, followed by dialysis against PBS.

Immunogen: This PACSIN2 antibody is generated from a mouse immunized with a recombinant protein between 250-486 amino acids from human PACSIN2.

Clone: 1735CT116-76-60

Isotype: IgG1 kappa

Application Details

Application Notes: WB: 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

Target Details for PACSIN2

Target: PACSIN2 (Protein Kinase C and Casein Kinase Substrate in Neurons 2 (PACSIN2))

Alternative Name: PACSIN2 (PACSIN2 Products)

Background: Lipid-binding protein that is able to promote the tubulation of the phosphatidic acid-containing membranes it preferentially binds. Plays a role in intracellular vesicle- mediated transport. Involved in the endocytosis of cell-surface receptors like the EGF receptor, contributing to its internalization in the absence of EGF stimulus. May also play a role in the formation of caveolae at the cell membrane. Recruits DNM2 to caveolae, and thereby plays a role in caveola-mediated endocytosis.

Molecular Weight: 55739

UniProt: Q9UNF0