PFN1 antibody (C-Term)

Catalog No. ABIN6242520

The Rabbit Polyclonal anti-PFN1 antibody has been validated for WB. It is suitable to detect PFN1 in samples from Human.

Quick Overview for PFN1 antibody (C-Term) (ABIN6242520)

Target: PFN1 (Profilin 1 (PFN1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PFN1 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB49649

Product Details anti-PFN1 Antibody

Binding Specificity: AA 87-120, C-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This PFN1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 87-120 amino acids from the C-terminal region of human PFN1.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:8000. WB: 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

Target Details for PFN1

Target: PFN1 (Profilin 1 (PFN1))

Alternative Name: PFN1

Background: Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG. Inhibits androgen receptor (AR) and HTT aggregation and binding of G-actin is essential for its inhibition of AR.

Molecular Weight: 15054

UniProt: P07737

Pathways: Regulation of Actin Filament Polymerization, Tube Formation, Maintenance of Protein Location