Tetraspanin 6 antibody (C-Term)

Catalog No. ABIN6242668

This anti-Tetraspanin 6 antibody is a Rabbit Polyclonal antibody detecting Tetraspanin 6 in WB and FACS. Suitable for Human and Mouse. This Primary Antibody has been cited in 2+ publications.

Quick Overview for Tetraspanin 6 antibody (C-Term) (ABIN6242668)

Target: Tetraspanin 6 (TSPAN6)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Tetraspanin 6 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Clone: RB23234

Product Details anti-Tetraspanin 6 Antibody

Binding Specificity: AA 176-205, C-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This TSPAN6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 176~205 amino acids from the C-terminal region of human TSPAN6.

Isotype: IgG

Application Details

Application Notes: WB: 1:1000. WB: 1:1000. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-Tetraspanin 6 antibody (ABIN6242668)

Salas, Callaerts-Vegh, Arranz, Guix, DHooge, Esteban, De Strooper, Dotti: "Tetraspanin 6: A novel regulator of hippocampal synaptic transmission and long term plasticity." in: PLoS ONE, Vol. 12, Issue 2, pp. e0171968, (2017) (PubMed).

Guix, Sannerud, Berditchevski, Arranz, Horré, Snellinx, Thathiah, Saido, Saito, Rajesh, Overduin, Kumar-Singh, Radaelli, Corthout, Colombelli, Tosi, Munck, Salas, Annaert, De Strooper: "Tetraspanin 6: a pivotal protein of the multiple vesicular body determining exosome release and lysosomal degradation of amyloid precursor protein fragments." in: Molecular neurodegeneration, Vol. 12, Issue 1, pp. 25, (2017) (PubMed).

Target Details for Tetraspanin 6

Target: Tetraspanin 6 (TSPAN6)

Alternative Name: TSPAN6

Background: The protein is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein and is highly similar in sequence to the transmembrane 4 superfamily member 2.

Molecular Weight: 27563

NCBI Accession: NP_001265672, NP_003261

UniProt: O43657