IL23A antibody (AA 33-67)

Catalog No. ABIN6242802

The Rabbit Polyclonal anti-IL23A antibody has been validated for WB and FACS. It is suitable to detect IL23A in samples from Human and Mouse.

Quick Overview for IL23A antibody (AA 33-67) (ABIN6242802)

Target: IL23A (Interleukin 23, alpha subunit p19 (IL23A))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL23A antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Clone: RB56752

Product Details anti-IL23A Antibody

Binding Specificity: AA 33-67

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This IL23A antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 33-67 amino acids from the Central region of human IL23A.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:2000. FC: 1:25

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

Target Details for IL23A

Target: IL23A (Interleukin 23, alpha subunit p19 (IL23A))

Alternative Name: IL23A

Background: Associates with IL12B to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak- Stat signaling cascade, stimulates memory rather than naive T- cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.

Molecular Weight: 20730

UniProt: Q9NPF7

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation