MLL3 antibody

Catalog No. ABIN6242807

This Mouse Monoclonal antibody specifically detects MLL3 in WB. It exhibits reactivity toward Human.

Quick Overview for MLL3 antibody (ABIN6242807)

Target: MLL3 (KMT2C) (Histone-lysine N-methyltransferase 2C (KMT2C))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This MLL3 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: 1686CT202-60-69

Product Details anti-MLL3 Antibody

Purification: This antibody is purified through a protein G column, followed by dialysis against PBS.

Immunogen: This MLL3 antibody is generated from a mouse immunized with a recombinant protein of human MLL3.

Isotype: IgG1 kappa

Application Details

Application Notes: WB: 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

Target Details for MLL3

Target: MLL3 (KMT2C) (Histone-lysine N-methyltransferase 2C (KMT2C))

Alternative Name: MLL3

Background: Histone methyltransferase. Methylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Central component of the MLL2/3 complex, a coactivator complex of nuclear receptors, involved in transcriptional coactivation. KMT2C/MLL3 may be a catalytic subunit of this complex. May be involved in leukemogenesis and developmental disorder.

Molecular Weight: 541370

UniProt: Q8NEZ4

Pathways: Warburg Effect