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MLL3 antibody (C-Term)

KMT2C Reactivity: Human IHC (p) Host: Rabbit Polyclonal RB52486 unconjugated
Catalog No. ABIN6242808
  • Target See all MLL3 (KMT2C) products
    MLL3 (KMT2C) (Histone-lysine N-methyltransferase 2C (KMT2C))
    Binding Specificity
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 3784-3818, C-Term
    Reactivity
    Human
    Host
    • 9
    • 1
    Rabbit
    Clonality
    • 9
    • 1
    Polyclonal
    Conjugate
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MLL3 antibody is un-conjugated
    Application
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This MLL3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 3784-3818 amino acids from the C-terminal region of human MLL3.
    Clone
    RB52486
    Isotype
    Ig Fraction
  • Application Notes
    IHC-P: 1:25
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Expiry Date
    6 months
  • Target
    MLL3 (KMT2C) (Histone-lysine N-methyltransferase 2C (KMT2C))
    Alternative Name
    MLL3 (KMT2C Products)
    Synonyms
    HALR antibody, MLL3 antibody, E330008K23Rik antibody, Mll3 antibody, mKIAA1506 antibody, lysine methyltransferase 2C antibody, lysine (K)-specific methyltransferase 2C antibody, KMT2C antibody, Kmt2c antibody
    Background
    Histone methyltransferase. Methylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Central component of the MLL2/3 complex, a coactivator complex of nuclear receptors, involved in transcriptional coactivation. KMT2C/MLL3 may be a catalytic subunit of this complex. May be involved in leukemogenesis and developmental disorder.
    Molecular Weight
    541370
    UniProt
    Q8NEZ4
    Pathways
    Warburg Effect
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