MLL3 antibody (C-Term)

Catalog No. ABIN6242808

The Rabbit Polyclonal anti-MLL3 antibody has been validated for IHC (p). It is suitable to detect MLL3 in samples from Human.

Quick Overview for MLL3 antibody (C-Term) (ABIN6242808)

Target: MLL3 (KMT2C) (Histone-lysine N-methyltransferase 2C (KMT2C))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MLL3 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB52486

Product Details anti-MLL3 Antibody

Binding Specificity: AA 3784-3818, C-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This MLL3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 3784-3818 amino acids from the C-terminal region of human MLL3.

Isotype: Ig Fraction

Application Details

Application Notes: IHC-P: 1:25

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

Target Details for MLL3

Target: MLL3 (KMT2C) (Histone-lysine N-methyltransferase 2C (KMT2C))

Alternative Name: MLL3

Background: Histone methyltransferase. Methylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Central component of the MLL2/3 complex, a coactivator complex of nuclear receptors, involved in transcriptional coactivation. KMT2C/MLL3 may be a catalytic subunit of this complex. May be involved in leukemogenesis and developmental disorder.

Molecular Weight: 541370

UniProt: Q8NEZ4

Pathways: Warburg Effect