GIT1 antibody (C-Term, Tyr554)

Catalog No. ABIN6242999

This Rabbit Polyclonal antibody specifically detects GIT1 in WB and FACS. It exhibits reactivity toward Human and Mouse.

Quick Overview for GIT1 antibody (C-Term, Tyr554) (ABIN6242999)

Target: GIT1

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GIT1 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Clone: RB15351

Product Details anti-GIT1 Antibody

Binding Specificity: AA 533-561, C-Term, Tyr554

Predicted Reactivity: Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This GIT1-Y554 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 533-561 amino acids from the C-terminal region of human GIT1-Y554.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:2000. WB: 1:1000. WB: 1:1000. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

Target Details for GIT1

Target: GIT1

Alternative Name: GIT1

Background: GTPase-activating protein for the ADP ribosylation factor family. May serve as a scaffold to bring together molecules to form signaling modules controlling vesicle trafficking, adhesion and cytoskeletal organization. Increases the speed of cell migration, as well as the size and rate of formation of protrusions, possibly by targeting PAK1 to adhesions and the leading edge of lamellipodia. Sequesters inactive non-tyrosine-phosphorylated paxillin in cytoplasmic complexes (from SwissProt).

Molecular Weight: 84341

NCBI Accession: NP_001078923, NP_054749

UniProt: Q9Y2X7