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IGF2R antibody (AA 2424-2458)
This Rabbit Polyclonal antibody specifically detects IGF2R in WB. It exhibits reactivity toward Human.
Quick Overview for IGF2R antibody (AA 2424-2458) (ABIN6243098)
Target
See all IGF2R Antibodies
IGF2R
(Insulin-Like Growth Factor 2 Receptor (IGF2R))
Reactivity
All reactivities for IGF2R antibodies
Human
Host
All hosts for IGF2R antibodies
Rabbit
Clonality
All clonalities for IGF2R antibodies
Polyclonal
Conjugate
All conjugates for IGF2R antibodies
This IGF2R antibody is un-conjugated
Application
All applications for IGF2R antibodies
Western Blotting (WB)
Clone
RB54531
Product Details anti-IGF2R Antibody
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Binding Specificity
All epitopes for IGF2R antibodies
AA 2424-2458
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This IGF2R antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 2424-2458 amino acids from human IGF2R.
Isotype
Ig Fraction
Alternatives
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Application Details
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Application Notes
WB: 1:2000
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Expiry Date
6 months
Target Details for IGF2R
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Target
IGF2R
(Insulin-Like Growth Factor 2 Receptor (IGF2R))
Alternative Name
IGF2R
Background
Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6- phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex. This receptor also binds IGF2. Acts as a positive regulator of T-cell coactivation, by binding DPP4.
Molecular Weight
274375
UniProt
P11717
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