SLC7A5 antibody (AA 15-45)

Catalog No. ABIN6243100

The Rabbit Polyclonal anti-SLC7A5 antibody (Clone RB55305) (ABIN6243100) specifically detects SLC7A5 in WB and IF. The antibody is reactive with Human samples.

Quick Overview for SLC7A5 antibody (AA 15-45) (ABIN6243100)

Target: SLC7A5 (Solute Carrier Family 7 (Cationic Amino Acid Transporter, Y+ System), Member 5 (SLC7A5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC7A5 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Clone: RB55305

Product Details anti-SLC7A5 Antibody

Binding Specificity: AA 15-45

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This SLC7A5 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 15-45 amino acids from human SLC7A5.

Isotype: Ig Fraction

Application Details

Application Notes: IF: 1:25. WB: 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

Target Details for SLC7A5

Target: SLC7A5 (Solute Carrier Family 7 (Cationic Amino Acid Transporter, Y+ System), Member 5 (SLC7A5))

Alternative Name: SLC7A5

Background: Sodium-independent, high-affinity transport of large neutral amino acids such as phenylalanine, tyrosine, leucine, arginine and tryptophan, when associated with SLC3A2/4F2hc. Involved in cellular amino acid uptake. Acts as an amino acid exchanger. Involved in the transport of L-DOPA across the blood- brain barrier, and that of thyroid hormones triiodothyronine (T3) and thyroxine (T4) across the cell membrane in tissues such as placenta. Plays a role in neuronal cell proliferation (neurogenesis) in brain. Involved in the uptake of methylmercury (MeHg) when administered as the L-cysteine or D,L-homocysteine complexes, and hence plays a role in metal ion homeostasis and toxicity. Involved in the cellular activity of small molecular weight nitrosothiols, via the stereoselective transport of L- nitrosocysteine (L-CNSO) across the transmembrane. May play an important role in high-grade gliomas. Mediates blood-to-retina L- leucine transport across the inner blood-retinal barrier which in turn may play a key role in maintaining large neutral amino acids as well as neurotransmitters in the neural retina. Acts as the major transporter of tyrosine in fibroblasts.

Molecular Weight: 55010

UniProt: Q01650